Congenital hemolytic anemia

Congenital hemolytic anemia (or hereditary hemolytic anemia) refers to hemolytic anemia which is primarily due to congenital disorders.^[1]

Types

Basically classified by causative mechanism , types of congenital hemolytic anemia include:

• Genetic conditions of RBC Membrane
  • Hereditary spherocytosis
  • Hereditary elliptocytosis
• Genetic conditions of RBC metabolism (enzyme defects). This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding hemoglobin abdormalities as well, but rather encompassing defects of glycolysis in the erythrocyte.^[2]
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD or favism)
  • Pyruvate kinase deficiency
• Hemoglobinopathies^[3]/genetic conditions of hemoglobin
  • Sickle cell anemia
  • Congenital dyserythropoietic anemia
  • Thalassemia

See also

• Hematopoietic ulcer
• List of circulatory system conditions

References